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What is Ostarine (MK-2866)?
Ostarine is classified as a SARM or selective androgen receptor modulator. It is also known as enobosarm, MK-2866, S-22 and GTx-024. Ostarine is produced by GTx, Inc. The pharmaceutical company is headquartered at Memphis in Tennessee. Ostarine was earlier developed by Merck & Company for its potential use of specific conditions such as osteoporosis and muscle wasting.
Ostarine is categorized as an investigational new drug in the United States. It has an elimination half-life of twenty-four hours. The IUPAC name of the drug is ((2S)-3-(4-cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide). CAS Number of Ostarine is 841205-47-8, its PubChem CID is 11326715, ChemSpider is 9501667, UNII is O3571H3R8N and KEGG is D10221. The chemical formula of the drug is C19H14F3N3O3. It has a molar mass of 389.33g/mol and its melting point is 270°F to 277°F or 132°C to 136°C.
History of Ostarine
GTx, Inc. was established in 1997. It was granted the right to develop enobosarm by the University of Tennessee Research Foundation. The inventors of enobosarm are Michael Whitt and Karen Veverka and both went on to join the pharmaceutical company. Enobosarm underwent several phases of trials from circa 2005 through 2014. Ostarine was studied and tested for its effectiveness against different medical conditions including curing wasting in patients suffering from lung cancer. The drug has also been tested to cure urinary incontinence caused by stress. GTx, Inc. has clarified in a paper published in 2009 that MK 2866 is not Andarine. MK-2866 was perceived to have the same chemical structure as of S-4, which is actually Andarine.
Ostarine or Enobosarm vs. SARMs
SARMs are banned by various international and global sporting regulatory authorities including the World Anti-Doping Agency. Historically, SARMs have been used by sportspersons and athletes to enhance their stamina or endurance, fitness, and strength. SARMs work like anabolic steroids. However, Ostarine is not strictly a SARM. It is an investigative SARM. It has a specific purpose and it does not work exactly as anabolic steroids.
Medical Purpose of Ostarine or Enobosarm
MK 2866 or enobosarm is now available as a health supplement. There are drugs and dietary supplements that contain enobosarm or ostarine. The medical purpose of this drug is to increase strength and muscle mass. It is owing to this reason that the drug or the investigational SARM can prevent muscle wasting, even treat it. MK 2866 is recommended by many to cure muscle atrophy. The drug is also good for the bones, especially strength and density. The SARM can also prevent certain conditions of the heart.
Enobosarm or ostarine can bind to hormone receptors and work like anabolic steroids but the impact is limited. MK 2866 can increase muscle mass, strengthen bones, reduce bad cholesterol, enhance insulin resistance and support heart function. There may be some side effects, especially back pain and headaches. Ostarine cannot be used by professional athletes and sportspersons if they are planning to participate at major tournaments. Fitness enthusiasts and bodybuilders can consider it as a supplement. Those suffering from muscle atrophy, osteoporosis, high cholesterol, and heart problems may consider MK 2866 as a drug.
Benefits of MK 2866
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brutalforce.com The most noteworthy benefit of ostarine is its impact on mass and strength in your muscles. Women and men, especially older adults, suffer from muscle wasting. Muscle atrophy is often natural and at times aided by aging, lifestyle, medication or failing health. Reduced muscle mass can impair physical functions including limiting the range of motion and movement. Enobosarm or ostarine supplements can undo these. SARMs are effective at increasing the lean mass in muscles. Formation of muscles and sustaining their growth are aided by ostarine supplementation, thereby improving muscle function and movement.
Osteoporosis is a specific condition characterized by weak and brittle bones. While mostly associated with aging and sedentary lifestyles, osteoporosis can also develop in relatively young adults and those who may otherwise appear to be healthy. MK-2866 supplementation can stimulate the healing of the bones. Stronger muscles also help in this regeneration. Fractures, hairline cracks and other problems of the bones can also be helped to heal quicker with mk 2866 supplementation.
MK 2866 supports heart function because of its impact on muscle mass. Weakened muscles would have an adverse effect on the quintessential functioning of the heart. Depending on the dose of ostarine, the drug can reduce the level of bad cholesterol in your blood. Taking an appropriate dose of MK-2866 daily can help elderly men and postmenopausal women to reduce the levels of blood glucose. The insulin resistance is reduced by MK-2866, which is often necessary among the aging and the elderly.
Side Effects of Ostarine
MK-2866 has high bioavailability and its absorption is not a problem for the human body. Ostarine does not have any severe side effects but some people may experience back pain and headaches. Ostarine supplementation is not allowed for athletes, certainly not during competition. Ostarine does not have any major interaction with other drugs. However, it is safe to be sure so you must consult your doctor to understand how the medicines you are taking already may or may not interfere with ostarine supplementation. It is difficult to generalize.
Ostarine is a patented drug & supplement. The exact chemical structure is not known. How much of it is used in products, drugs or supplements, is often disclosed but other ingredients are not known? There are many trademarks and brand names that use ostarine as one of the compounds but it may not be apparent at the outset. It is necessary to buy MK 2866 in its typical drug form or as a supplement that does not have any other unsafe ingredient. MK-2866 is mostly recommended for people suffering from muscle atrophy, also known as muscle wasting.
Muscles have a tendency to lose some of the mass in due course of time. This also results in the loss of form. Muscles can suffer this loss of mass for many reasons. Some people are genetically predisposed to have weaker muscles. Some people may not get adequate nutrition. Different diseases have an impact on the muscles. Muscle atrophy is limited to people who have naturally short or small muscles in certain parts. For instance, a muscle in the right arm may be smaller than one in the left arm. A muscle at the back may be unusually smaller than that in other people. It is possible there is only one small or short muscle compared to an average human of the same age, gender, and race. It is also possible there are several muscles affected by wasting or atrophy. It is not always just the size or form but also the volume, density, and strength. Muscle atrophy is often associated with poor density, lack of sufficient strength and a significantly slow tissue regeneration process.
Anyone suffering from muscle wasting must consult a doctor. Diet, exercise and physical therapy are the first responses but they may fail to address atrophy completely. While some people may experience a positive change with diet, exercise, and therapy, others may need supplementation. This is where enobosarm comes in. Muscle wasting is a chronic condition if it is left unattended. While you can treat it and even reverse the damage caused entirely if you act fast and counter muscle atrophy in its earliest phases, you may not be able to help it if it has worsened beyond a point of cure or redemption.
Muscle wasting or atrophy has many symptoms. Fatigue or lethargy is common. There would be a visible loss of mass. There can be more than one cause of muscle atrophy and only an extensive diagnosis would be able to reveal if it is inactivity, aging, an aftermath of a stroke, alcoholism, malnutrition, injury to the spine or bones, specific diseases such as amyotrophic lateral sclerosis, neuropathy, polio, osteoarthritis and rheumatoid arthritis or something else. The entire medical history of a person is assessed to determine the cause and to chart out a course of treatment.
Ostarine is recommended by many doctors to cure muscle atrophy. There are many brands of ostarine or supplements that contain it. It is best to go with the specific type of enobosarm that your doctor recommends. The doctor would prescribe a certain dose and it would be wise to follow the instructions specifically. It is not healthy to change the dosage or the course without the approval of the supervising doctor. It can be purchased at stores or online. Prices would vary depending on where you buy it from. Always buy from a trusted source.
Conclusion
Mk 2866 is not only capable of undoing the damage caused by muscle atrophy but it can also help in sustaining the new mass gained in your muscles. Hence, ostarine may be prescribed for a substantial period of time. The exact duration of the course will depend on the severity of muscle atrophy and how one responds to the drug or supplement. As is the case with other drugs and not just selective androgen receptor modulators, MK-2866 has varied effects and not everyone will experience the same turnaround within identical timelines.
MK2866 stacks great with Ligandrol.